XanthaLean

Our XanthaLean fat burning supplement is formulated to help support weight management by decreasing fat cell production, the expression of adipogenic genes, white adipose tissue, and secretion of triglycerides, while increasing metabolism.

This fat burning supplement also provides the body with antioxidants to help eliminate toxins stored in fat cells from the body. Pollutants and toxins are released throughout the body upon lipolysis. Therefore weight loss can lead to more toxins circulating throughout the body. Antioxidants are required to help quench these toxins and reduce damage.

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Recommended Dosage:
For Adults Ages 19+: Take 1 capsule 3x/day, 15-30 minutes before each meal.

Cautions & Warnings:
• Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding.
• Consult a health care practitioner prior to use if you are diabetic.

Any questions contact our Customer Service Team at 1-800-852-5401

Medicinal Ingredients:
Xanthigen® Proprietary Blend, Brown Seaweed extract (200:1) (Undaria pinnatifida), Pomegranate seed oil extract (110:1) (Punica granatum)

Non-medicinal Ingredients:
Gelatin, Glycerin, Purified Water, Olive Oil.

Orders over $99 get FREE expedited shipping anywhere in Canada.

For orders under $99, shipping costs vary by order depending on your location. All shipping costs will be calculated prior to your checkout in the cart section. All products are shipped via Canada Post.

Click HERE to see an estimated delivery date based on your postal code.

If you are unsatisfied with your Herbal Magic products for any reason we will give you a refund of your purchase price for all unopened merchandise, less shipping. Simply email customerservice@herbalmagic.ca within seven (7) days of receipt of your order to obtain a Return Merchandise Authorization (RMA#). Please write the number on the package. Include the packing slip that came with your order, and wrap the package securely. Ship to the return address indicated on the shipping label. If you do not have your packing slip, please indicate the order number on a separate piece of paper, enclose in the package and send the package to the following address:

Herbal Magic
6600 Dixie Rd, Unit 2
Mississauga ON L5T 2Y2 
Canada
1-800-852-5401

Research
Research suggests that xanthigen® has been clinically tested to support healthy weight management and fat metabolism. In a double-blind, randomized, placebo-controlled trial involving 151 women following an 1800 calorie per day diet, participants were randomly assigned to receive Xanthigen®, fucoxanthin, pomegranate seed oil or olive oil (placebo) for 16 weeks. Results demonstrated that those in the Xanthigen® group had an average weight loss of 14.5 pounds compared to 3 pounds in the placebo group. Xanthigen® also supported healthy hepatic fat metabolism, healthy triglyceride levels and healthy C-reactive protein (CRP) levels.7,8,9

Research also shows that fucoxanthin and punicic acid in combination help better suppress adipocyte differentiation and lipid accumulation via multiple pathways, than either alone. Xanthigen®, a combination of both active ingredients, helps suppress accumulation of lipid droplets in adipocytes compared to its individual components.10

The Brown Seaweed (Fucoxanthin) in this product is rich in fucoxanthin, a type of carotenoid (a class of natural pigments found in brown seaweed) antioxidant that protects cells and tissues from damaging effects of free radicals. Fucoxanthin has demonstrated slimming properties by reducing fat storage11,12,13 It is also a source of omega-3 fatty acids which have recognized triglyceride lowering effects. 14 Fucoxanthin has shown weight loss properties by increasing energy expenditure and promoting fat burning within fat cells, by upregulating mitochondrial uncoupling protein 1 (UCP1).1 UCP1 expression is known as a significant component of whole body energy expenditure and its dysfunction contributes to the development of obesity. 15,16Fucoxanthin is also known for its anti-inflammatory, anti-cancer, anti-diabetic, anti-angiogenic and anti-malarial activities, and its protective effects on the liver, blood vessels of the brain, bones, skin, and eyes.17

Pomegranate Seed (Punicic Acid) contains the active nutrient ingredient punicic acid, which is known to have several health benefits, including high antioxidant capacity, anti-inflamatory, antitumor, immunomodulatory, anti-atherosclerotic and serum lipid-lowering activities.15,17,18 Pucinic Acid is derived from pomegranate seed and supports epidermal tissue regeneration, boosts the immune system and displays chemopreventative activity against hormone related (prostate and breast) and colon cancers.15 Punicic Acid has also been shown to suppress the production and secretion of triglycerides and apolipoproteins.19 Research shows that Punicic Acid can help reduce triglycerides in hyperlipidemic adults and create a favorable HDL: TG ratio20, decrease fat accumulation synergistically in adipocytes cultures21 and modulate genes facilitating insulin and glucose metabolism in muscle cultures and inhibited pro-inflammatory genes.22

Resources
1 Elobeid MA, Padilla MA, Brock DW, Ruden DM, Allison DB. Endocrine disruptors and obesity: an examination of selected persistent organic pollutants in the NHANES 1999-2002 data. Int J Environ Res Public Health. 2010 July 7(7):2988-3005.
2 Hue O, Marcotte J, Berrigan F, Simoneau M, Doré J, Marceau P, Marceau S, Tremblay A, Teasdale N. Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery. Obes Surg. 2006 September 16(9):1145-54.
3 Charlier C, Desaive C, Plomteux G. Human exposure to endocrine disrupters: consequences of gastroplasty on plasma concentration of toxic pollutants. nt J Obes Relat Metab Disord. 2002 November ;26(11):1465-8.
Clinical Toxicology Laboratory, University Hospital, Liege, Belgium.
4 Lim JS, Son HK, Park SK, Jacobs DR Jr, Lee DH. Int J Obes (Lond). Inverse associations between long-term weight change and serum concentrations of persistent organic pollutants.2011;35(5):744-7.
5 Fang YZ, Yang S, Wu G. Free radicals, antioxidants, and nutrition. Nutrition. 2002 Oct;18(10):872-9.
6 Uttara B, Singh AV, Zamboni P, Mahajan R. Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options. Current Neuropharmacology. 2009;7(1):65-74.
7 Abidov, M., Siefulla, R., & Ramazanov, Z. (2008). The effect of Xanthigen™, a phytomedicine containing fucoxanthin and pomegranate seed oil, on body weight and liver fat, serum triglycerides, C-reactive protein, and plasma aminotransferases in obese non-diabetic female volunteers: a double-blind, randomized and placebo-controlled trial. Submitted for publication. Int J Obesity.
8 Abidov, M., & Roshen, S. (2008). Effect of Fucoxanthin and Xanthigen™, a phytomedicine containing fucoxanthin and pomegranate seed oil, on energy expenditure rate in obese non-diabetic female volunteers with non-alcoholic fatty liver disease: a double-blind, randomized and placebo-controlled trial. Submitted for publication. Int J Obesity.
9 Abidov, M., Ramazanov, Z., Seifulla, R., & Grachev, S. (2010). The effects of Xanthigen™ in the weight management of obese premenopausal women with non‐alcoholic fatty liver disease and normal liver fat. Diabetes, obesity and metabolism, 12(1), 72-81.
10 Ching-Shu Lai et al. Xanthigen Suppresses Preadipocyte Differentiation and Adipogenesis through Down-regulation of PPARγ and C/EBPs and Modulation of SIRT-1, AMPK, and FoxO Pathways. J. Agric. Food Chem. 2012;60(4):1094–1101.
11> Brown LJ, et al (2002). Normal thyroid thermogenesis but reduced viability and adiposity in mice lacking the mitochondrial glycerol phosphate dehydrogenase. J Biol Chem 277: 32892–32898.
12 Nicholls DG, Locke RM (1984). Thermogenic mechanisms in brown fat. Physiol Rev 64: 1–64.
13 Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K (2006). Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Int J Mol Med 18(1): 147–152.
14 Tsuku T, et al (2007). Fucoxanthin and fucoxanthinol enhance the amount of docosahexanoic acid in the liver of KKAy obese/diabetic mice. J Agric Food Chem Jun 27; 55(13):5025-9. 15 Maeda H et al (2005). Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochem Biophys Res Commun 332(2): 392–397.
16 B.B. Lowell, V. S-Susullc, A. Hamann, J.A. Lawitts, J. HimmaHagen, B.B. Boyer, L.P. Kozak, J.S. Flier, Development of obesity in transgenic mice after genetic ablation of brown adipose tissue, Nature 366 (1993) 740–742.
17 Melo I., Carvalho E., Mancini-Filho J., Pomegranate Seed Oil (Punica Granatum L.): A Source of Punicic Acid (Conjugated alpha-Linolenic Acid). J Hum Nutr Food Sci 2014;2(1):1024.
18 Peng J., Yuan J-P., et al. Fucoanthin, a Marine Carotenoid Present in Brown Seaweeeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health. Mar.Drugs. 2011;9:1806-1828.
19 Arao K, et al (2004). The 9cis, 11trans, 13cis isomer of conjugated linolenic acid reduces apolipoprotein B100 secretion and triacylglycerol synthesis in HepG2 cells. Biosci Biotechnol Biochem 68: 395–397.
20 Parvin Mirmiran, Mohammad Reza Fazeli, Golaleh Asghari, Abbas Shafiee and Fereidoun Azizi (2010). Effect of pomegranate seed oil on hyperlipidaemic subjects: a double-blind placebo-controlled clinical trial. British Journal of Nutrition, 104, pp 402-406.
21 Lai CS, Tsai ML, Badmaev V, Jimenez M, Ho CT, Pan MH. Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARγ and C/EBPs and modulation of SIRT-1, AMPK, and FoxO pathways. J Agric Food Chem. 2012 Feb 1;60(4):1094-101.
22 Gammone MA, D'Orazio N. Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin. Mar. Drugs 2015, 13(4), 2196-2214.